Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps3-30-05 | Thyroid Physiology in Periphery & Development Basic | ETA2023

Acute T3 administration reduces myocardial infarct size

Pape Janina , Grund Susanne , Piwellek Kristina , Lorenz Kristina , Langhauser Friederike , Mittag Jens , Christian Moller Lars , Fuhrer Dagmar

As thyroid hormones (TH) are essential for the normal heart function, a low TH state in ischemic cardiovascular events is often correlated to a poor prognosis. While clinical and experimental data suggests that TH intervention in acute myocardial infarction might be beneficial, a detailed insight in the mechanisms on TH action in IR injury or post infarct recovery of the heart is still lacking. In this study, we examined the effect of thyroid hormone pre- and postconditioning ...